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High-Level Production, Solubilization and Purification of Synthetic Human GPCR Chemokine Receptors CCR5, CCR3, CXCR4 and CX3CR1

Chemokine receptors belong to a class of integral membrane G-protein coupled receptors (GPCRs) and are responsible for transmitting signals from the extracellular environment. However, the structural changes in the receptor, connecting ligand binding to G-protein activation, remain elusive for most...

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Detalles Bibliográficos
Autores principales:	Ren, Hui, Yu, Daoyong, Ge, Baosheng, Cook, Brian, Xu, Zhinan, Zhang, Shuguang
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637981/ https://www.ncbi.nlm.nih.gov/pubmed/19223978 http://dx.doi.org/10.1371/journal.pone.0004509

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