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Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome
Protein tyrosine phosphatases (PTPs) play a critical role in regulating cellular functions by selectively dephosphorylating their substrates. Here we present 22 human PTP crystal structures that, together with prior structural knowledge, enable a comprehensive analysis of the classical PTP family. D...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638020/ https://www.ncbi.nlm.nih.gov/pubmed/19167335 http://dx.doi.org/10.1016/j.cell.2008.11.038 |