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Myogenic Akt signaling upregulates the utrophin–glycoprotein complex and promotes sarcolemma stability in muscular dystrophy

Duchenne muscular dystrophy is caused by dystrophin mutations that lead to structural instability of the sarcolemma membrane, myofiber degeneration/regeneration and progressive muscle wasting. Here we show that myogenic Akt signaling in mouse models of dystrophy promotes increased expression of utro...

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Detalles Bibliográficos
Autores principales:	Peter, Angela K., Ko, Christopher Y., Kim, Michelle H., Hsu, Nigel, Ouchi, Noriyuki, Rhie, Suhn, Izumiya, Yasuhiro, Zeng, Ling, Walsh, Kenneth, Crosbie, Rachelle H.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638781/ https://www.ncbi.nlm.nih.gov/pubmed/18986978 http://dx.doi.org/10.1093/hmg/ddn358

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