Reciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autism

Mutations in MECP2, encoding methyl-CpG-binding protein 2 (MeCP2), cause the neurodevelopmental disorder Rett syndrome (RTT). Although MECP2 mutations are rare in idiopathic autism, reduced MeCP2 levels are common in autism cortex. MeCP2 is critical for postnatal neuronal maturation and a modulator...

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Detalles Bibliográficos
Autores principales: Swanberg, Susan E., Nagarajan, Raman P., Peddada, Sailaja, Yasui, Dag H., LaSalle, Janine M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638799/
https://www.ncbi.nlm.nih.gov/pubmed/19000991
http://dx.doi.org/10.1093/hmg/ddn380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638799/
https://www.ncbi.nlm.nih.gov/pubmed/19000991
http://dx.doi.org/10.1093/hmg/ddn380

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