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Interactions between the juvenile Batten disease gene, CLN3, and the Notch and JNK signalling pathways

Mutations in the gene CLN3 are responsible for the neurodegenerative disorder juvenile neuronal ceroid lipofuscinosis or Batten disease. CLN3 encodes a multi-spanning and hydrophobic transmembrane protein whose function is unclear. As a consequence, the cell biology that underlies the pathology of t...

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Detalles Bibliográficos
Autores principales:	Tuxworth, Richard I., Vivancos, Valérie, O'Hare, Megan B., Tear, Guy
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638826/ https://www.ncbi.nlm.nih.gov/pubmed/19028667 http://dx.doi.org/10.1093/hmg/ddn396

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