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IL-2 receptor γ chain cytokines differentially regulate human CD8(+)CD127(+) and CD8(+)CD127(−) T cell division and susceptibility to apoptosis
Expression of IL-7 receptor α (CD127) is associated with naive and memory (i.e. non-effector) CD8(+) T cell phenotypes. Effector CD8(+) T cells are predominantly CD127(−) and most die by apoptosis. Therefore, CD127 appears to be a marker for CD8(+) T cell differentiation, yet its role in CD8(+) T ce...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638842/ https://www.ncbi.nlm.nih.gov/pubmed/19011158 http://dx.doi.org/10.1093/intimm/dxn120 |