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Quantitative PET reporter gene imaging of CD8(+) T cells specific for a melanoma-expressed self-antigen
Adoptive transfer (AT) T-cell therapy provides significant clinical benefits in patients with advanced melanoma. However, approaches to non-invasively visualize the persistence of transferred T cells are lacking. We examined whether positron emission tomography (PET) can monitor the distribution of...
Autores principales: | Shu, Chengyi J., Radu, Caius G., Shelly, Stephanie M., Vo, Dan D., Prins, Robert, Ribas, Antoni, Phelps, Michael E., Witte, Owen N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638874/ https://www.ncbi.nlm.nih.gov/pubmed/19106231 http://dx.doi.org/10.1093/intimm/dxn133 |
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