Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance

AIMS: Duchenne muscular dystrophy (DMD) is a severe and still incurable disease, with heart failure as a leading cause of death. The identification of a disease-modifying therapy may require early-initiated and long-term administration, but such type of therapeutic trial is not evident in humans. We...

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Detalles Bibliográficos
Autores principales: Buyse, Gunnar M., Van der Mieren, Gerry, Erb, Michael, D'hooge, Jan, Herijgers, Paul, Verbeken, Erik, Jara, Alejandro, Van Den Bergh, An, Mertens, Luc, Courdier-Fruh, Isabelle, Barzaghi, Patrizia, Meier, Thomas
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Preclinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639086/
https://www.ncbi.nlm.nih.gov/pubmed/18784063
http://dx.doi.org/10.1093/eurheartj/ehn406

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