Position-dependent motif characterization using non-negative matrix factorization

Motivation: Cis-acting regulatory elements are frequently constrained by both sequence content and positioning relative to a functional site, such as a splice or polyadenylation site. We describe an approach to regulatory motif analysis based on non-negative matrix factorization (NMF). Whereas exist...

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Detalles Bibliográficos
Autores principales: Hutchins, Lucie N., Murphy, Sean M., Singh, Priyam, Graber, Joel H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639279/
https://www.ncbi.nlm.nih.gov/pubmed/18852176
http://dx.doi.org/10.1093/bioinformatics/btn526

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