Size matters: just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiology

Background Despite earlier doubts, a string of recent successes indicates that if sample sizes are large enough, it is possible—both in theory and in practice—to identify and replicate genetic associations with common complex diseases. But human genome epidemiology is expensive and, from a strategic...

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Detalles Bibliográficos
Autores principales: Burton, Paul R, Hansell, Anna L, Fortier, Isabel, Manolio, Teri A, Khoury, Muin J, Little, Julian, Elliott, Paul
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Theory and Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639365/
https://www.ncbi.nlm.nih.gov/pubmed/18676414
http://dx.doi.org/10.1093/ije/dyn147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639365/
https://www.ncbi.nlm.nih.gov/pubmed/18676414
http://dx.doi.org/10.1093/ije/dyn147

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