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Size matters: just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiology
Background Despite earlier doubts, a string of recent successes indicates that if sample sizes are large enough, it is possible—both in theory and in practice—to identify and replicate genetic associations with common complex diseases. But human genome epidemiology is expensive and, from a strategic...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639365/ https://www.ncbi.nlm.nih.gov/pubmed/18676414 http://dx.doi.org/10.1093/ije/dyn147 |