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Arp2/3 complex activity in filopodia of spreading cells
BACKGROUND: Cells use filopodia to explore their environment and to form new adhesion contacts for motility and spreading. The Arp2/3 complex has been implicated in lamellipodial actin assembly as a major nucleator of new actin filaments in branched networks. The interplay between filopodial and lam...
Autores principales: | Johnston, Simon A, Bramble, Jonathan P, Yeung, Chun L, Mendes, Paula M, Machesky, Laura M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639383/ https://www.ncbi.nlm.nih.gov/pubmed/19068115 http://dx.doi.org/10.1186/1471-2121-9-65 |
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