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Upregulation of prolylcarboxypeptidase (PRCP) in lipopolysaccharide (LPS) treated endothelium promotes inflammation

BACKGROUND: Prolylcarboxypeptidase (Prcp) gene, along with altered PRCP and kallikrein levels, have been implicated in inflammation pathogenesis. PRCP regulates angiotensin 1–7 (Ang 1–7) – and bradykinin (BK) – stimulated nitric oxide production in endothelial cells. The mechanism through which kall...

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Detalles Bibliográficos
Autores principales:	Ngo, My-Linh, Mahdi, Fakhri, Kolte, Dhaval, Shariat-Madar, Zia
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639534/ https://www.ncbi.nlm.nih.gov/pubmed/19171072 http://dx.doi.org/10.1186/1476-9255-6-3

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