PTEN and rapamycin inhibiting the growth of K562 cells through regulating mTOR signaling pathway

OBJECTIVE: To investigate, in vitro, the regulatory effects of tumor-suppressing gene PTEN on mTOR (mammalian target of rapamycin) signaling pathway, the effects of transfected PTEN and rapamycin on the growth inhibition, and apoptosis induction for human leukemia cell line K562 cells. METHODS: K562...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Zhi Y, Guo, Xiao L, Yang, Xiao Y, Niu, Zhi Y, Li, Shi H, Wang, Su Y, Chen, Hao, Pan, Ling
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639541/
https://www.ncbi.nlm.nih.gov/pubmed/19115995
http://dx.doi.org/10.1186/1756-9966-27-87

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639541/
https://www.ncbi.nlm.nih.gov/pubmed/19115995
http://dx.doi.org/10.1186/1756-9966-27-87

Ejemplares similares