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Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for molecules associated with metabolism, signaling and regulation in central nervous system mixed glial cell cultures
BACKGROUND: Cytokines secreted by immune cells and activated glia play central roles in both the pathogenesis of and protection from damage to the central nervous system (CNS) in multiple sclerosis (MS). METHODS: We have used gene array analysis to identify the initial direct effects of cytokines on...
Autores principales: | Lisak, Robert P, Benjamins, Joyce A, Bealmear, Beverly, Nedelkoska, Liljana, Studzinski, Diane, Retland, Ernest, Yao, Bin, Land, Susan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639549/ https://www.ncbi.nlm.nih.gov/pubmed/19159481 http://dx.doi.org/10.1186/1742-2094-6-4 |
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