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Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells
BACKGROUND: Effective transvascular delivery of nanoparticle-based chemotherapeutics across the blood-brain tumor barrier of malignant gliomas remains a challenge. This is due to our limited understanding of nanoparticle properties in relation to the physiologic size of pores within the blood-brain...
Autores principales: | Sarin, Hemant, Kanevsky, Ariel S, Wu, Haitao, Brimacombe, Kyle R, Fung, Steve H, Sousa, Alioscka A, Auh, Sungyoung, Wilson, Colin M, Sharma, Kamal, Aronova, Maria A, Leapman, Richard D, Griffiths, Gary L, Hall, Matthew D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639552/ https://www.ncbi.nlm.nih.gov/pubmed/19094226 http://dx.doi.org/10.1186/1479-5876-6-80 |
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