Multivariate profiling of neurodegeneration-associated changes in a subcellular compartment of neurons via image processing

BACKGROUND: Dysfunction in the endolysosome, a late endosomal to lysosomal degradative intracellular compartment, is an early hallmark of some neurodegenerative diseases, in particular Alzheimer's disease. However, the subtle morphological changes in compartments of affected neurons are difficu...

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Detalles Bibliográficos
Autores principales: Kumarasamy, Saravana K, Wang, Yunshi, Viswanathan, Vignesh, Kraut, Rachel S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639580/
https://www.ncbi.nlm.nih.gov/pubmed/19014586
http://dx.doi.org/10.1186/1756-0381-1-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639580/
https://www.ncbi.nlm.nih.gov/pubmed/19014586
http://dx.doi.org/10.1186/1756-0381-1-10

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