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Multivariate profiling of neurodegeneration-associated changes in a subcellular compartment of neurons via image processing
BACKGROUND: Dysfunction in the endolysosome, a late endosomal to lysosomal degradative intracellular compartment, is an early hallmark of some neurodegenerative diseases, in particular Alzheimer's disease. However, the subtle morphological changes in compartments of affected neurons are difficu...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639580/ https://www.ncbi.nlm.nih.gov/pubmed/19014586 http://dx.doi.org/10.1186/1756-0381-1-10 |