The Structure of Phosphorylase Kinase Holoenzyme at 9.9 Å Resolution and Location of the Catalytic Subunit and the Substrate Glycogen Phosphorylase

Phosphorylase kinase (PhK) coordinates hormonal and neuronal signals to initiate the breakdown of glycogen. The enzyme catalyzes the phosphorylation of inactive glycogen phosphorylase b (GPb), resulting in the formation of active glycogen phosphorylase a. We present a 9.9 Å resolution structure of P...

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Detalles Bibliográficos
Autores principales: Vénien-Bryan, Catherine, Jonic, Slavica, Skamnaki, Vasiliki, Brown, Nick, Bischler, Nicolas, Oikonomakos, Nikos G., Boisset, Nicolas, Johnson, Louise N.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639635/
https://www.ncbi.nlm.nih.gov/pubmed/19141288
http://dx.doi.org/10.1016/j.str.2008.10.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639635/
https://www.ncbi.nlm.nih.gov/pubmed/19141288
http://dx.doi.org/10.1016/j.str.2008.10.013

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