Molecular docking studies on DMDP derivatives as human DHFR inhibitors

Molecular docking is routinely used for understanding drug‐receptor interaction in modern drug design. Here, we describe the docking of 2, 4-diamino-5-methyl-5-deazapteridine (DMDP) derivatives as inhibitors to human dihydrofolate reductase (DHFR). We docked 78 DMDP derivates collected from literatu...

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Detalles Bibliográficos
Autores principales: Srivastava, Vivek, Kumar, Ashutosh, Mishra, Bhartendu Nath, Siddiqi, Mohammad Imran
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2008
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639668/
https://www.ncbi.nlm.nih.gov/pubmed/19238244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639668/
https://www.ncbi.nlm.nih.gov/pubmed/19238244

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