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Systematic identification of cis-silenced genes by trans complementation

A gene’s transcriptional output is the combined product of two inputs: diffusible factors in the cellular milieu acting in trans, and chromatin state acting in cis. Here, we describe a strategy for dissecting the relative contribution of cis versus trans mechanisms to gene regulation. Referred to as...

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Detalles Bibliográficos
Autores principales: Lee, Jae Hyun, Bugarija, Branimir, Millan, Enrique J., Walton, Noah M., Gaetz, Jedidiah, Fernandes, Croydon J., Yu, Wei-Hua, Mekel-Bobrov, Nitzan, Vallender, Tammy W., Snyder, Gregory E., Xiang, Andy Peng, Lahn, Bruce T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640206/
https://www.ncbi.nlm.nih.gov/pubmed/19050040
http://dx.doi.org/10.1093/hmg/ddn409