Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling

Failure of oligodendrocyte precursor cell (OPC) differentiation contributes significantly to failed myelin sheath regeneration (remyelination) in chronic demyelinating diseases. Although the reasons for this failure are not completely understood, several lines of evidence point to factors present fo...

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Detalles Bibliográficos
Autores principales: Baer, Alexandra S., Syed, Yasir A., Kang, Sung Ung, Mitteregger, Dieter, Vig, Raluca, ffrench-Constant, Charles, Franklin, Robin J. M., Altmann, Friedrich, Lubec, Gert, Kotter, Mark R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640211/
https://www.ncbi.nlm.nih.gov/pubmed/19208690
http://dx.doi.org/10.1093/brain/awn334

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