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Bacterial symbiosis in arthropods and the control of disease transmission.

Bacterial symbionts may be used as vehicles for expressing foreign genes in arthropods. Expression of selected genes can render an arthropod incapable of transmitting a second microorganism that is pathogenic for humans and is an alternative approach to the control of arthropod-borne diseases. We di...

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Detalles Bibliográficos
Autores principales: Beard, C B, Durvasula, R V, Richards, F F
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640264/
https://www.ncbi.nlm.nih.gov/pubmed/9866734
Descripción
Sumario:Bacterial symbionts may be used as vehicles for expressing foreign genes in arthropods. Expression of selected genes can render an arthropod incapable of transmitting a second microorganism that is pathogenic for humans and is an alternative approach to the control of arthropod-borne diseases. We discuss the rationale for this alternative approach, its potential applications and limitations, and the regulatory concerns that may arise from its use in interrupting disease transmission in humans and animals.