Peptide length significantly influences in vitro affinity for MHC class II molecules

BACKGROUND: Class II Major Histocompatibility Complex (MHC) molecules have an open-ended binding groove which can accommodate peptides of varying lengths. Several studies have demonstrated that peptide flanking residues (PFRs) which lie outside the core binding groove can influence peptide binding a...

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Detalles Bibliográficos
Autores principales: O'Brien, Cathal, Flower, Darren R, Feighery, Conleth
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640366/
https://www.ncbi.nlm.nih.gov/pubmed/19036163
http://dx.doi.org/10.1186/1745-7580-4-6

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