Investigating Differential Dynamics of the MAPK Signaling Cascade Using a Multi-Parametric Global Sensitivity Analysis

Cell growth critically depends on signalling pathways whose regulation is the focus of intense research. Without utilizing a priori knowledge of the relative importance of pathway components, we have applied in silico computational methods to the EGF-induced MAPK cascade. Specifically, we systematic...

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Detalles Bibliográficos
Autores principales: Yoon, Jeongah, Deisboeck, Thomas S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640453/
https://www.ncbi.nlm.nih.gov/pubmed/19234599
http://dx.doi.org/10.1371/journal.pone.0004560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640453/
https://www.ncbi.nlm.nih.gov/pubmed/19234599
http://dx.doi.org/10.1371/journal.pone.0004560

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