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Developing tTA Transgenic Rats for Inducible and Reversible Gene Expression

To develop transgenic lines for conditional expression of desired genes in rats, we generated several lines of the transgenic rats carrying the tetracycline-controlled transactivator (tTA) gene. Using a vigorous, ubiquitous promoter to drive the tTA transgene, we obtained widespread expression of tT...

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Detalles Bibliográficos
Autores principales: Zhou, Hongxia, Huang, Cao, Yang, Min, Landel, Carlisle P, Xia, Pedro Yuxing, Liu, Yong-Jian, Xia, Xu Gang
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640494/
https://www.ncbi.nlm.nih.gov/pubmed/19214245