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Cell-Autonomous Requirement for Rx Function in the Mammalian Retina and Posterior Pituitary

Rx is a paired-like homeobox gene that is required for vertebrate eye formation. Mice lacking Rx function do not develop eyes or the posterior pituitary. To determine whether Rx is required cell autonomously in these tissues, we generated embryonic chimeras consisting of wild type and Rx−/− cells. W...

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Detalles Bibliográficos
Autores principales: Medina-Martinez, Olga, Amaya-Manzanares, Felipe, Liu, Chaomei, Mendoza, Marisela, Shah, Rina, Zhang, Li, Behringer, Richard R., Mahon, Kathleen A., Jamrich, Milan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2641000/
https://www.ncbi.nlm.nih.gov/pubmed/19229337
http://dx.doi.org/10.1371/journal.pone.0004513

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