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Cell-Autonomous Requirement for Rx Function in the Mammalian Retina and Posterior Pituitary
Rx is a paired-like homeobox gene that is required for vertebrate eye formation. Mice lacking Rx function do not develop eyes or the posterior pituitary. To determine whether Rx is required cell autonomously in these tissues, we generated embryonic chimeras consisting of wild type and Rx−/− cells. W...
Autores principales: | Medina-Martinez, Olga, Amaya-Manzanares, Felipe, Liu, Chaomei, Mendoza, Marisela, Shah, Rina, Zhang, Li, Behringer, Richard R., Mahon, Kathleen A., Jamrich, Milan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2641000/ https://www.ncbi.nlm.nih.gov/pubmed/19229337 http://dx.doi.org/10.1371/journal.pone.0004513 |
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