Transcription Factor Binding Sites Are Genetic Determinants of Retroviral Integration in the Human Genome

Gamma-retroviruses and lentiviruses integrate non-randomly in mammalian genomes, with specific preferences for active chromatin, promoters and regulatory regions. Gene transfer vectors derived from gamma-retroviruses target at high frequency genes involved in the control of growth, development and d...

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Detalles Bibliográficos
Autores principales: Felice, Barbara, Cattoglio, Claudia, Cittaro, Davide, Testa, Anna, Miccio, Annarita, Ferrari, Giuliana, Luzi, Lucilla, Recchia, Alessandra, Mavilio, Fulvio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642719/
https://www.ncbi.nlm.nih.gov/pubmed/19238208
http://dx.doi.org/10.1371/journal.pone.0004571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642719/
https://www.ncbi.nlm.nih.gov/pubmed/19238208
http://dx.doi.org/10.1371/journal.pone.0004571

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