Cargando…

Focal adhesion kinase (FAK) expression and activation during lens development

PURPOSE: Regulation of lens development involves an intricate interplay between growth factor (e.g. FGF and TGFβ) and extracellular matrix (ECM) signaling pathways. Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase that plays key roles in transmitting ECM signals by integrins. In this stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kokkinos, Maria I., Brown, Heidi J., de Iongh, Robbert U.
Formato:	Texto
Lenguaje:	English
Publicado:	Molecular Vision 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642935/ https://www.ncbi.nlm.nih.gov/pubmed/17417603

Ejemplares similares

Focal Adhesion Kinase (FAK) Over-Expression and Prognostic Implication in Pediatric Hepatocellular Carcinoma
por: Francalanci, Paola, et al.
Publicado: (2020)

Simiate and the focal adhesion kinase FAK1 cooperate in the regulation of dendritogenesis
por: Rama, Ramya, et al.
Publicado: (2022)

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions
Publicado: (1993)

Daurinol blocks breast and lung cancer metastasis and development by inhibition of focal adhesion kinase (FAK)
por: Woo, Jong Kyu, et al.
Publicado: (2017)

ZINC40099027 activates human focal adhesion kinase by accelerating the enzymatic activity of the FAK kinase domain
por: Rashmi,, et al.
Publicado: (2021)

Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart
por: Hirth, Sofia, et al.
Publicado: (2016)

The roles of nuclear focal adhesion kinase (FAK) on Cancer: a focused review
por: Zhou, Jin, et al.
Publicado: (2019)

The direct effect of Focal Adhesion Kinase (FAK), dominant-negative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis
por: Golubovskaya, Vita M, et al.
Publicado: (2009)

Caspase-mediated Cleavage of Focal Adhesion Kinase pp125(FAK) and Disassembly of Focal Adhesions in Human Endothelial Cell Apoptosis
por: Levkau, Bodo, et al.
Publicado: (1998)

SAT-574 Elucidating the Role of Nuclear Focal Adhesion Kinase (FAK) in Thyroid Cancer
por: Kellett, Meghan, et al.
Publicado: (2019)

Drug Discovery Targeting Focal Adhesion Kinase (FAK) as a Promising Cancer Therapy
por: Pang, Xiao-Jing, et al.
Publicado: (2021)

Focal Adhesion Kinase (FAK) tyrosine 397E mutation restores the vascular leakage defect in endothelium‐specific FAK‐kinase dead mice
por: Alexopoulou, Annika N, et al.
Publicado: (2017)

Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells
por: Rigiracciolo, Damiano Cosimo, et al.
Publicado: (2019)

Downregulation of Focal Adhesion Kinase (FAK) by cord blood stem cells inhibits angiogenesis in glioblastoma
por: Dasari, Venkata Ramesh, et al.
Publicado: (2010)

Identification of Novel Focal Adhesion Kinase Substrates: Role for FAK in NFκB Signaling
por: Dwyer, Sheila Figel, et al.
Publicado: (2015)

Prognostic Value of Focal Adhesion Kinase (FAK) in Human Solid Carcinomas: A Meta-Analysis
por: Zeng, Xiao-Qing, et al.
Publicado: (2016)

Hyperphosphorylated FAK Delocalizes from Focal Adhesions to Membrane Ruffles
por: Hamadi, Abdelkader, et al.
Publicado: (2010)

Cortactin as a Target for FAK in the Regulation of Focal Adhesion Dynamics
por: Tomar, Alok, et al.
Publicado: (2012)

FAK and paxillin dynamics at focal adhesions in the protrusions of migrating cells
por: Hu, Ying-Li, et al.
Publicado: (2014)

FAK Structure and Regulation by Membrane Interactions and Force in Focal Adhesions
por: Tapial Martínez, Paula, et al.
Publicado: (2020)

Activation of the integrins α5β1 and αvβ3 and focal adhesion kinase (FAK) during arteriogenesis
por: Cai, Wei-Jun, et al.
Publicado: (2008)

Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity
por: Kishi, Takayuki, et al.
Publicado: (2016)

Focal Adhesion Kinase (FAK) Inhibition Synergizes with KRAS G12C Inhibitors in Treating Cancer through the Regulation of the FAK–YAP Signaling
por: Zhang, Baoyuan, et al.
Publicado: (2021)

Molecular dynamics simulation analysis of Focal Adhesive Kinase (FAK) docked with solanesol as an anti-cancer agent
por: Daneial, Betty, et al.
Publicado: (2017)

Direct association of pp125FAK with paxillin, the focal adhesion- targeting mechanism of pp125FAK
Publicado: (1995)

β1 Integrin-Focal Adhesion Kinase (FAK) Signaling Modulates Retinal Ganglion Cell (RGC) Survival
por: Santos, Andrea Rachelle C., et al.
Publicado: (2012)

Vascular growth responses to chronic arterial occlusion are unaffected by myeloid specific focal adhesion kinase (FAK) deletion
por: Heuslein, Joshua L., et al.
Publicado: (2016)

pH sensing by FAK-His58 regulates focal adhesion remodeling
por: Choi, Chang-Hoon, et al.
Publicado: (2013)

MiR-7a is an important mediator in Fas-associated protein with death domain (FADD)-regulated expression of focal adhesion kinase (FAK)
por: Liu, Yingting, et al.
Publicado: (2016)

Mycosporine-Like Amino Acids Promote Wound Healing through Focal Adhesion Kinase (FAK) and Mitogen-Activated Protein Kinases (MAP Kinases) Signaling Pathway in Keratinocytes
por: Choi, Yun-Hee, et al.
Publicado: (2015)

Osteoprotegerin (OPG) activates integrin, focal adhesion kinase (FAK), and Akt signaling in ovarian cancer cells to attenuate TRAIL-induced apoptosis
por: Lane, Denis, et al.
Publicado: (2013)

A novel drug-like water-soluble small molecule Focal Adhesion Kinase (FAK) activator promotes intestinal mucosal healing
por: Wang, Qinggang, et al.
Publicado: (2022)

The focal adhesion protein Hic-5 is highly expressed in the rat myometrium during late pregnancy and labour and co-localizes with FAK
por: Croke, Jenn M, et al.
Publicado: (2007)

Focal Adhesion Kinase (FAK) Mediates the Induction of Pro-Oncogenic and Fibrogenic Phenotypes in Hepatitis C Virus (HCV)-Infected Cells
por: Alisi, Anna, et al.
Publicado: (2012)

Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility
por: Wang, Wenqi, et al.
Publicado: (2011)

FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion
por: Chan, Keefe T., et al.
Publicado: (2009)

Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair
por: Zhou, Dennis W., et al.
Publicado: (2021)

High expression of focal adhesion kinase (p125(FAK)) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome
por: Schmitz, Klaus Jürgen, et al.
Publicado: (2005)

FAK/src-Family Dependent Activation of the Ste20-Like Kinase SLK Is Required for Microtubule-Dependent Focal Adhesion Turnover and Cell Migration
por: Wagner, Simona, et al.
Publicado: (2008)

Focal Adhesion Kinases in Adhesion Structures and Disease
por: Eleniste, Pierre P., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_urobhtrmsbfi79lcrfd5nn4ior