Integrative Analysis of Epigenetic Modulation in Melanoma Cell Response to Decitabine: Clinical Implications

Decitabine, an epigenetic modifier that reactivates genes otherwise suppressed by DNA promoter methylation, is effective for some, but not all cancer patients, especially those with solid tumors. It is commonly recognized that to overcome resistance and improve outcome, treatment should be guided by...

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Detalles Bibliográficos
Autores principales: Halaban, Ruth, Krauthammer, Michael, Pelizzola, Mattia, Cheng, Elaine, Kovacs, Daniela, Sznol, Mario, Ariyan, Stephan, Narayan, Deepak, Bacchiocchi, Antonella, Molinaro, Annette, Kluger, Yuval, Deng, Min, Tran, Nam, Zhang, Wengeng, Picardo, Mauro, Enghild, Jan J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642998/
https://www.ncbi.nlm.nih.gov/pubmed/19234609
http://dx.doi.org/10.1371/journal.pone.0004563

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