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Probing Evolutionary Repeatability: Neutral and Double Changes and the Predictability of Evolutionary Adaptation
BACKGROUND: The question of how organisms adapt is among the most fundamental in evolutionary biology. Two recent studies investigated the evolution of Escherichia coli in response to challenge with the antibiotic cefotaxime. Studying five mutations in the β-lactamase gene that together confer signi...
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643001/ https://www.ncbi.nlm.nih.gov/pubmed/19234610 http://dx.doi.org/10.1371/journal.pone.0004500 |