Improved Learning and Memory in Aged Mice Deficient in Amyloid β-Degrading Neutral Endopeptidase

BACKGROUND: Neutral endopeptidase, also known as neprilysin and abbreviated NEP, is considered to be one of the key enzymes in initial human amyloid-β (Aβ) degradation. The aim of our study was to explore the impact of NEP deficiency on the initial development of dementia-like symptoms in mice. METH...

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Detalles Bibliográficos
Autores principales: Walther, Thomas, Albrecht, Doris, Becker, Matthias, Schubert, Manja, Kouznetsova, Elena, Wiesner, Burkard, Maul, Björn, Schliebs, Reinhard, Grecksch, Gisela, Furkert, Jens, Sterner-Kock, Anja, Schultheiss, Heinz-Peter, Becker, Axel, Siems, Wolf-Eberhard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643003/
https://www.ncbi.nlm.nih.gov/pubmed/19240795
http://dx.doi.org/10.1371/journal.pone.0004590

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