Mitogen Activated Protein Kinase Activated Protein Kinase 2 Regulates Actin Polymerization and Vascular Leak in Ventilator Associated Lung Injury

Mechanical ventilation, a fundamental therapy for acute lung injury, worsens pulmonary vascular permeability by exacting mechanical stress on various components of the respiratory system causing ventilator associated lung injury. We postulated that MK2 activation via p38 MAP kinase induced HSP25 pho...

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Detalles Bibliográficos
Autores principales: Damarla, Mahendra, Hasan, Emile, Boueiz, Adel, Le, Anne, Pae, Hyun Hae, Montouchet, Calypso, Kolb, Todd, Simms, Tiffany, Myers, Allen, Kayyali, Usamah S., Gaestel, Matthias, Peng, Xinqi, Reddy, Sekhar P., Damico, Rachel, Hassoun, Paul M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643011/
https://www.ncbi.nlm.nih.gov/pubmed/19240800
http://dx.doi.org/10.1371/journal.pone.0004600

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