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Genetic risk factors for variant Creutzfeldt–Jakob disease: a genome-wide association study

BACKGROUND: Human and animal prion diseases are under genetic control, but apart from PRNP (the gene that encodes the prion protein), we understand little about human susceptibility to bovine spongiform encephalopathy (BSE) prions, the causal agent of variant Creutzfeldt–Jakob disease (vCJD). METHOD...

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Detalles Bibliográficos
Autores principales:	Mead, Simon, Poulter, Mark, Uphill, James, Beck, John, Whitfield, Jerome, Webb, Thomas EF, Campbell, Tracy, Adamson, Gary, Deriziotis, Pelagia, Tabrizi, Sarah J, Hummerich, Holger, Verzilli, Claudio, Alpers, Michael P, Whittaker, John C, Collinge, John
Formato:	Texto
Lenguaje:	English
Publicado:	Lancet Pub. Group 2009
Materias:	Fast track — Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643048/ https://www.ncbi.nlm.nih.gov/pubmed/19081515 http://dx.doi.org/10.1016/S1474-4422(08)70265-5

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