Uptake of the antifungal cationic peptide Histatin 5 by Candida albicans Ssa2p requires binding to non-conventional sites within the ATPase domain

Candida albicans Hsp70 Ssa1/2 proteins have been identified as cell wall binding partners for the antifungal cationic peptide Histatin 5 (Hst 5) in vivo. C. albicans Ssa2p plays a major role in binding and translocation of Hst 5 into fungal cells, as demonstrated by defective peptide uptake and kill...

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Detalles Bibliográficos
Autores principales: Sun, Jianing N, Li, Wansheng, Jang, Woong Sik, Nayyar, Namrata, Sutton, Mark D, Edgerton, Mira
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643122/
https://www.ncbi.nlm.nih.gov/pubmed/19006817
http://dx.doi.org/10.1111/j.1365-2958.2008.06480.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643122/
https://www.ncbi.nlm.nih.gov/pubmed/19006817
http://dx.doi.org/10.1111/j.1365-2958.2008.06480.x

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