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Regulation of C-type Lectin Antimicrobial Activity by a Flexible N-terminal Prosegment

Members of the RegIII family of intestinal C-type lectins are directly antibacterial proteins that play a vital role in maintaining host-bacterial homeostasis in the mammalian gut, yet little is known about the mechanisms that regulate their biological activity. Here we show that the antibacterial a...

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Detalles Bibliográficos
Autores principales:	Mukherjee, Sohini, Partch, Carrie L., Lehotzky, Rebecca E., Whitham, Cecilia V., Chu, Hiutung, Bevins, Charles L., Gardner, Kevin H., Hooper, Lora V.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2009
Materias:	Protein Synthesis, Post-Translational Modification, and Degradation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643518/ https://www.ncbi.nlm.nih.gov/pubmed/19095652 http://dx.doi.org/10.1074/jbc.M808077200

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