Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

The ErbB signaling pathways, which regulate diverse physiological responses such as cell survival, proliferation and motility, have been subjected to extensive molecular analysis. Nonetheless, it remains poorly understood how different ligands induce different responses and how this is affected by o...

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Detalles Bibliográficos
Autores principales: Chen, William W, Schoeberl, Birgit, Jasper, Paul J, Niepel, Mario, Nielsen, Ulrik B, Lauffenburger, Douglas A, Sorger, Peter K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644173/
https://www.ncbi.nlm.nih.gov/pubmed/19156131
http://dx.doi.org/10.1038/msb.2008.74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644173/
https://www.ncbi.nlm.nih.gov/pubmed/19156131
http://dx.doi.org/10.1038/msb.2008.74

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