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Secretion of MCP-1 and other paracrine factors in a novel tumor-bone coculture model
BACKGROUND: The bone-tumor microenvironment encompasses unique interactions between the normal cells of the bone and marrow cavity and the malignant cells from a primary or metastasized cancer. A multitude of paracrine factors within this microenvironment such as the growth factor, TGF-β, and the ch...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644314/ https://www.ncbi.nlm.nih.gov/pubmed/19192289 http://dx.doi.org/10.1186/1471-2407-9-45 |