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Secretion of MCP-1 and other paracrine factors in a novel tumor-bone coculture model

BACKGROUND: The bone-tumor microenvironment encompasses unique interactions between the normal cells of the bone and marrow cavity and the malignant cells from a primary or metastasized cancer. A multitude of paracrine factors within this microenvironment such as the growth factor, TGF-β, and the ch...

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Detalles Bibliográficos
Autores principales: Schiller, Katherine R, Zillhardt, Marion R, Alley, Jeremy, Borjesson, Dori L, Beitz, Alvin J, Mauro, Laura J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644314/
https://www.ncbi.nlm.nih.gov/pubmed/19192289
http://dx.doi.org/10.1186/1471-2407-9-45