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Dissociation of tau toxicity and phosphorylation: role of GSK-3β, MARK and Cdk5 in a Drosophila model

Hyperphosphorylation of tau at multiple sites has been implicated in the formation of neurofibrillary tangles in Alzheimer’s disease; however, the relationship between toxicity and phosphorylation of tau has not been clearly elucidated. Putative tau kinases that play a role in such phosphorylation e...

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Detalles Bibliográficos
Autores principales: Chatterjee, Shreyasi, Sang, Tzu-Kang, Lawless, George M., Jackson, George R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644648/
https://www.ncbi.nlm.nih.gov/pubmed/18930955
http://dx.doi.org/10.1093/hmg/ddn326

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