The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16(INK4a)

BACKGROUND: CDKN2A/p16(INK4a )is frequently altered in human cancers and it is the most important melanoma susceptibility gene identified to date. p16(INK4a )inhibits pRb phosphorylation and induces cell cycle arrest, which is considered its main tumour suppressor function. Nevertheless, additional...

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Detalles Bibliográficos
Autores principales: Becker, Therese M, Haferkamp, Sebastian, Dijkstra, Menno K, Scurr, Lyndee L, Frausto, Monika, Diefenbach, Eve, Scolyer, Richard A, Reisman, David N, Mann, Graham J, Kefford, Richard F, Rizos, Helen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644676/
https://www.ncbi.nlm.nih.gov/pubmed/19149898
http://dx.doi.org/10.1186/1476-4598-8-4

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