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Antioxidant properties of MitoTEMPOL and its hydroxylamine
Piperidine nitroxides such as TEMPOL have been widely used as antioxidants in vitro and in vivo. MitoTEMPOL is a mitochondria-targeted derivative of TEMPOL designed to protect mitochondria from the oxidative damage that they accumulate, but once there is rapidly reduced to its hydroxylamine, MitoTEM...
Autores principales: | Trnka, Jan, Blaikie, Frances H., Logan, Angela, Smith, Robin A. J., Murphy, Michael P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645131/ https://www.ncbi.nlm.nih.gov/pubmed/19058062 http://dx.doi.org/10.1080/10715760802582183 |
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