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Dacron(® )vs. PTFE as bypass materials in peripheral vascular surgery – systematic review and meta-analysis
BACKGROUND: In peripheral vascular bypass surgery different synthetic materials are available for bypass grafting. It is unclear which of the two commonly used materials, polytetrafluoroethylene (PTFE) or polyester (Dacron(®)) grafts, is to be preferred. Thus, the aim of this meta-analysis and syste...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645354/ https://www.ncbi.nlm.nih.gov/pubmed/19099583 http://dx.doi.org/10.1186/1471-2482-8-22 |
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author | Roll, Stephanie Müller-Nordhorn, Jacqueline Keil, Thomas Scholz, Hans Eidt, Daniela Greiner, Wolfgang Willich, Stefan N |
author_facet | Roll, Stephanie Müller-Nordhorn, Jacqueline Keil, Thomas Scholz, Hans Eidt, Daniela Greiner, Wolfgang Willich, Stefan N |
author_sort | Roll, Stephanie |
collection | PubMed |
description | BACKGROUND: In peripheral vascular bypass surgery different synthetic materials are available for bypass grafting. It is unclear which of the two commonly used materials, polytetrafluoroethylene (PTFE) or polyester (Dacron(®)) grafts, is to be preferred. Thus, the aim of this meta-analysis and systematic review was to compare the effectiveness of these two prosthetic bypass materials (Dacron(® )and PTFE). METHODS: We performed a systematic literature search in MEDLINE, Cochrane-Library – CENTRAL, EMBASE and other databases for relevant publications in English and German published between 1999 and 2008. Only randomized controlled trials were considered for inclusion. We assessed the methodological quality by means of standardized checklists. Primary patency was used as the main endpoint. Random-effect meta-analysis as well as pooling data in life table format was performed to combine study results. RESULTS: Nine randomized controlled trials (RCT) were included. Two trials showed statistically significant differences in primary patency, one favouring Dacron(® )and one favouring PTFE grafts, while 7 trials did not show statistically significant differences between the two materials. Meta-analysis on the comparison of PTFE vs. Dacron(® )grafts yielded no differences with regard to primary patency rates (hazard ratio 1.04 (95% confidence interval [0.85;1.28]), no significant heterogeneity (p = 0.32, I(2 )= 14%)). Similarly, there were no significant differences with regard to secondary patency rates. CONCLUSION: Systematic evaluation and meta-analysis of randomized controlled trials comparing Dacron(® )and PTFE as bypass materials for peripheral vascular surgery showed no evidence of an advantage of one synthetic material over the other. |
format | Text |
id | pubmed-2645354 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-26453542009-02-20 Dacron(® )vs. PTFE as bypass materials in peripheral vascular surgery – systematic review and meta-analysis Roll, Stephanie Müller-Nordhorn, Jacqueline Keil, Thomas Scholz, Hans Eidt, Daniela Greiner, Wolfgang Willich, Stefan N BMC Surg Research Article BACKGROUND: In peripheral vascular bypass surgery different synthetic materials are available for bypass grafting. It is unclear which of the two commonly used materials, polytetrafluoroethylene (PTFE) or polyester (Dacron(®)) grafts, is to be preferred. Thus, the aim of this meta-analysis and systematic review was to compare the effectiveness of these two prosthetic bypass materials (Dacron(® )and PTFE). METHODS: We performed a systematic literature search in MEDLINE, Cochrane-Library – CENTRAL, EMBASE and other databases for relevant publications in English and German published between 1999 and 2008. Only randomized controlled trials were considered for inclusion. We assessed the methodological quality by means of standardized checklists. Primary patency was used as the main endpoint. Random-effect meta-analysis as well as pooling data in life table format was performed to combine study results. RESULTS: Nine randomized controlled trials (RCT) were included. Two trials showed statistically significant differences in primary patency, one favouring Dacron(® )and one favouring PTFE grafts, while 7 trials did not show statistically significant differences between the two materials. Meta-analysis on the comparison of PTFE vs. Dacron(® )grafts yielded no differences with regard to primary patency rates (hazard ratio 1.04 (95% confidence interval [0.85;1.28]), no significant heterogeneity (p = 0.32, I(2 )= 14%)). Similarly, there were no significant differences with regard to secondary patency rates. CONCLUSION: Systematic evaluation and meta-analysis of randomized controlled trials comparing Dacron(® )and PTFE as bypass materials for peripheral vascular surgery showed no evidence of an advantage of one synthetic material over the other. BioMed Central 2008-12-19 /pmc/articles/PMC2645354/ /pubmed/19099583 http://dx.doi.org/10.1186/1471-2482-8-22 Text en Copyright © 2008 Roll et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Roll, Stephanie Müller-Nordhorn, Jacqueline Keil, Thomas Scholz, Hans Eidt, Daniela Greiner, Wolfgang Willich, Stefan N Dacron(® )vs. PTFE as bypass materials in peripheral vascular surgery – systematic review and meta-analysis |
title | Dacron(® )vs. PTFE as bypass materials in peripheral vascular surgery – systematic review and meta-analysis |
title_full | Dacron(® )vs. PTFE as bypass materials in peripheral vascular surgery – systematic review and meta-analysis |
title_fullStr | Dacron(® )vs. PTFE as bypass materials in peripheral vascular surgery – systematic review and meta-analysis |
title_full_unstemmed | Dacron(® )vs. PTFE as bypass materials in peripheral vascular surgery – systematic review and meta-analysis |
title_short | Dacron(® )vs. PTFE as bypass materials in peripheral vascular surgery – systematic review and meta-analysis |
title_sort | dacron(® )vs. ptfe as bypass materials in peripheral vascular surgery – systematic review and meta-analysis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645354/ https://www.ncbi.nlm.nih.gov/pubmed/19099583 http://dx.doi.org/10.1186/1471-2482-8-22 |
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