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Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death

BACKGROUND: Disturbed cellular cholesterol homeostasis may lead to accumulation of cholesterol in human atheroma plaques. Cellular cholesterol homeostasis is controlled by the sterol regulatory element-binding transcription factor 2 (SREBF-2) and the SREBF cleavage-activating protein (SCAP). We inve...

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Detalles Bibliográficos
Autores principales:	Fan, Yue-Mei, Karhunen, Pekka J, Levula, Mari, Ilveskoski, Erkki, Mikkelsson, Jussi, Kajander, Olli A, Järvinen, Otso, Oksala, Niku, Thusberg, Janita, Vihinen, Mauno, Salenius, Juha-Pekka, Kytömäki, Leena, Soini, Juhani T, Laaksonen, Reijo, Lehtimäki, Terho
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Original Clinical Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645360/ https://www.ncbi.nlm.nih.gov/pubmed/19116028 http://dx.doi.org/10.1186/1477-9560-6-17

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