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In vitro culture and somatic cell nuclear transfer affect imprinting of SNRPN gene in pre- and post-implantation stages of development in cattle
BACKGROUND: Embryo in vitro manipulations during early development are thought to increase mortality by altering the epigenetic regulation of some imprinted genes. Using a bovine interspecies model with a single nucleotide polymorphism, we assessed the imprinting status of the small nuclear ribonucl...
Autores principales: | Suzuki, Joao, Therrien, Jacinthe, Filion, France, Lefebvre, Rejean, Goff, Alan K, Smith, Lawrence C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645379/ https://www.ncbi.nlm.nih.gov/pubmed/19200381 http://dx.doi.org/10.1186/1471-213X-9-9 |
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