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Menin Interacts with IQGAP1 to Enhance Intercellular Adhesion of β Cells

Multiple endocrine neoplasia type 1 (MEN1) is a dominantly inherited tumor syndrome that results from the mutation of the MEN1 gene that encodes protein menin. Stable overexpression of MEN1 has been shown to partially suppress the RAS-mediated morphological changes of NH3 fibroblast cells. Little is...

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Detalles Bibliográficos
Autores principales: Yan, Jizhou, Yang, Yuqing, Zhang, Hui, King, Catrina, Kan, Ho-Man, Cai, Ying, Yuan, Chao-Xing, Bloom, George S, Hua, Xianxin
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645484/
https://www.ncbi.nlm.nih.gov/pubmed/19079338
http://dx.doi.org/10.1038/onc.2008.435