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Functional Analysis and Molecular Dynamics Simulation of LOX-1 K167N Polymorphism Reveal Alteration of Receptor Activity

The human lectin-like oxidized low density lipoprotein receptor 1 LOX-1, encoded by the ORL1 gene, is the major scavenger receptor for oxidized low density lipoprotein in endothelial cells. Here we report on the functional effects of a coding SNP, c.501G>C, which produces a single amino acid chan...

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Detalles Bibliográficos
Autores principales:	Biocca, Silvia, Falconi, Mattia, Filesi, Ilaria, Baldini, Francesco, Vecchione, Lucia, Mango, Ruggiero, Romeo, Francesco, Federici, Giorgio, Desideri, Alessandro, Novelli, Giuseppe
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645694/ https://www.ncbi.nlm.nih.gov/pubmed/19247493 http://dx.doi.org/10.1371/journal.pone.0004648

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