Cargando…

Elevated Levels of the Anti-Inflammatory Interleukin-1 Receptor Antagonist Precede the Onset of Type 2 Diabetes: The Whitehall II Study

OBJECTIVE—Interleukin-1 receptor antagonist (IL-1Ra), a natural inhibitor of interleukin-1β, has been shown to improve β-cell function and glycemic control in patients with type 2 diabetes. The aim of this study was to investigate whether baseline systemic levels of IL-1Ra are associated with incide...

Descripción completa

Detalles Bibliográficos
Autores principales:	Herder, Christian, Brunner, Eric J., Rathmann, Wolfgang, Strassburger, Klaus, Tabák, Adam G., Schloot, Nanette C., Witte, Daniel R.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Epidemiology/Health Services Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646020/ https://www.ncbi.nlm.nih.gov/pubmed/19073760 http://dx.doi.org/10.2337/dc08-1161

Ejemplares similares

Change in Sleep Duration and Type 2 Diabetes: The Whitehall II Study
por: Ferrie, Jane E., et al.
Publicado: (2015)

Accelerated Increase in Serum Interleukin-1 Receptor Antagonist Starts 6 Years Before Diagnosis of Type 2 Diabetes: Whitehall II Prospective Cohort Study
por: Carstensen, Maren, et al.
Publicado: (2010)

Dietary Patterns, Insulin Resistance, and Incidence of Type 2 Diabetes in the Whitehall II Study
por: McNaughton, Sarah A., et al.
Publicado: (2008)

The Systemic Immune Network in Recent Onset Type 1 Diabetes: Central Role of Interleukin-1 Receptor Antagonist (DIATOR Trial)
por: Kolb, Hubert, et al.
Publicado: (2013)

Patterns of Obesity Development before the Diagnosis of Type 2 Diabetes: The Whitehall II Cohort Study
por: Vistisen, Dorte, et al.
Publicado: (2014)

Adiponectin Trajectories Before Type 2 Diabetes Diagnosis: Whitehall II study
por: Tabák, Adam G., et al.
Publicado: (2012)

Decline in low-density lipoprotein cholesterol concentration: lipid-lowering drugs, diet, or physical activity? Evidence from the Whitehall II study
por: Bouillon, Kim, et al.
Publicado: (2011)

Adiponectin, biomarkers of inflammation and changes in cardiac autonomic function: Whitehall II study
por: Hansen, Christian Stevns, et al.
Publicado: (2017)

Determinants of Aortic Stiffness: 16-Year Follow-Up of the Whitehall II Study
por: Johansen, Nanna B., et al.
Publicado: (2012)

Association of aortic stiffness with cognitive decline: Whitehall II longitudinal cohort study
por: Araghi, Marzieh, et al.
Publicado: (2019)

Walking speed and subclinical atherosclerosis in healthy older adults: the Whitehall II study
por: Hamer, Mark, et al.
Publicado: (2010)

Effect of retirement on cognitive function: the Whitehall II cohort study
por: Xue, Baowen, et al.
Publicado: (2017)

Cardiovascular disease risk scores in identifying future frailty: the Whitehall II prospective cohort study
por: Bouillon, Kim, et al.
Publicado: (2013)

Nondiabetic Glucometabolic Status and Progression of Aortic Stiffness: The Whitehall II Study
por: McEniery, Carmel M., et al.
Publicado: (2017)

Reversion from prediabetes to normoglycaemia and risk of cardiovascular disease and mortality: the Whitehall II cohort study
por: Vistisen, Dorte, et al.
Publicado: (2019)

Hyperglycemia, Type 2 Diabetes, and Depressive Symptoms: The British Whitehall II study
por: Kivimaki, Mika, et al.
Publicado: (2009)

Blood pressure and site-specific cancer mortality: evidence from the original Whitehall study
por: Batty, G D, et al.
Publicado: (2003)

Effect of secular trends on age-related trajectories of cardiovascular risk factors: the Whitehall II longitudinal study 1985–2009
por: Hulmán, Adam, et al.
Publicado: (2014)

Association of renin and aldosterone with glucose metabolism in a Western European population: the KORA F4/FF4 study
por: Then, Cornelia, et al.
Publicado: (2022)

A statistical model to describe longitudinal and correlated metabolic risk factors: the Whitehall II prospective study
por: Breeze, P., et al.
Publicado: (2016)

Association between regional deprivation and type 2 diabetes incidence in Germany
por: Jacobs, Esther, et al.
Publicado: (2019)

Association between type 2 diabetes and chronic low back pain in general practices in Germany
por: Jacob, Louis, et al.
Publicado: (2021)

Differences in the prevalence of erectile dysfunction between novel subgroups of recent-onset diabetes
por: Maalmi, Haifa, et al.
Publicado: (2021)

Adiposity, Obesity, and Arterial Aging: Longitudinal Study of Aortic Stiffness in the Whitehall II Cohort
por: Brunner, Eric J., et al.
Publicado: (2015)

Socioeconomic Status and Reduced Kidney Function in the Whitehall II Study: Role of Obesity and Metabolic Syndrome
por: Al-Qaoud, Talal M., et al.
Publicado: (2011)

Physical Activity, Sedentary Behavior, and Long‐Term Changes in Aortic Stiffness: The Whitehall II Study
por: Ahmadi‐Abhari, Sara, et al.
Publicado: (2017)

Timing of onset of cognitive decline: results from Whitehall II prospective cohort study
por: Singh-Manoux, Archana, et al.
Publicado: (2012)

Heart Rate and Heart Rate Variability Changes Are Not Related to Future Cardiovascular Disease and Death in People With and Without Dysglycemia: A Downfall of Risk Markers? The Whitehall II Cohort Study
por: Hansen, Christian S., et al.
Publicado: (2021)

Age trajectories of glycaemic traits in non-diabetic South Asian and white individuals: the Whitehall II cohort study
por: Ikehara, Satoyo, et al.
Publicado: (2014)

Associations of Common Genetic Variants With Age-Related Changes in Fasting and Postload Glucose: Evidence From 18 Years of Follow-Up of the Whitehall II Cohort
por: Jensen, Anders C., et al.
Publicado: (2011)

Genetic Determinants of Circulating Interleukin-1 Receptor Antagonist Levels and Their Association With Glycemic Traits
por: Herder, Christian, et al.
Publicado: (2014)

Alternative Healthy Eating Index and mortality over 18 y of follow-up: results from the Whitehall II cohort(1)(2)(3)
por: Akbaraly, Tasnime N, et al.
Publicado: (2011)

Association of endothelial dysfunction with incident prediabetes, type 2 diabetes and related traits: the KORA F4/FF4 study
por: Huemer, Marie-Theres, et al.
Publicado: (2020)

Psychosocial Stress at Work Doubles the Risk of Type 2 Diabetes in Middle-Aged Women: Evidence from the Whitehall II Study
por: Heraclides, Alexandros, et al.
Publicado: (2009)

Trajectories of glycaemia, insulin sensitivity and insulin secretion in South Asian and white individuals before diagnosis of type 2 diabetes: a longitudinal analysis from the Whitehall II cohort study
por: Hulman, Adam, et al.
Publicado: (2017)

Traffic-Related Air Pollution and Incident Type 2 Diabetes: Results from the SALIA Cohort Study
por: Krämer, Ursula, et al.
Publicado: (2010)

Sitting Behavior and Obesity: Evidence from the Whitehall II Study
por: Pulsford, Richard M., et al.
Publicado: (2013)

Improved Preservation of Residual Beta Cell Function by Atorvastatin in Patients with Recent Onset Type 1 Diabetes and High CRP Levels (DIATOR Trial)
por: Strom, Alexander, et al.
Publicado: (2012)

Contribution of modifiable risk factors to social inequalities in type 2 diabetes: prospective Whitehall II cohort study
por: Stringhini, Silvia, et al.
Publicado: (2012)

Study protocol: the Whitehall II imaging sub-study
por: Filippini, Nicola, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_dmkikjk3v9t5v7sassnok9ifqq