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Primary Defects in β-Cell Function Further Exacerbated by Worsening of Insulin Resistance Mark the Development of Impaired Glucose Tolerance in Obese Adolescents

OBJECTIVE—Impaired glucose tolerance (IGT) is a pre-diabetic state of increasing prevalence among obese adolescents. The purpose of this study was to determine the natural history of progression from normal glucose tolerance (NGT) to IGT in obese adolescents. RESEARCH DESIGN AND METHODS—We determine...

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Detalles Bibliográficos
Autores principales:	Cali, Anna M.G., Man, Chiara Dalla, Cobelli, Claudio, Dziura, James, Seyal, Aisha, Shaw, Melissa, Allen, Karin, Chen, Shu, Caprio, Sonia
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Pathophysiology/Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646028/ https://www.ncbi.nlm.nih.gov/pubmed/19106382 http://dx.doi.org/10.2337/dc08-1274

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