Protein Kinase A Regulatory Subunits in Human Adipose Tissue: Decreased R2B Expression and Activity in Adipocytes From Obese Subjects

OBJECTIVE—In human adipocytes, the cAMP-dependent pathway mediates signals originating from β-adrenergic activation, thus playing a key role in the regulation of important metabolic processes, i.e., lipolysis and thermogenesis. Cyclic AMP effects are mainly mediated by protein kinase A (PKA), whose...

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Detalles Bibliográficos
Autores principales: Mantovani, Giovanna, Bondioni, Sara, Alberti, Luisella, Gilardini, Luisa, Invitti, Cecilia, Corbetta, Sabrina, Zappa, Marco A., Ferrero, Stefano, Lania, Andrea G., Bosari, Silvano, Beck-Peccoz, Paolo, Spada, Anna
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646060/
https://www.ncbi.nlm.nih.gov/pubmed/19095761
http://dx.doi.org/10.2337/db08-0585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646060/
https://www.ncbi.nlm.nih.gov/pubmed/19095761
http://dx.doi.org/10.2337/db08-0585

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