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Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss
OBJECTIVE—Obesity is associated with insulin resistance and type 2 diabetes, although the mechanisms linking these pathologies remain undetermined. Recent studies in rodent models revealed endoplasmic reticulum (ER) stress in adipose and liver tissues and demonstrated that ER stress could cause insu...
Autores principales: | Gregor, Margaret F., Yang, Ling, Fabbrini, Elisa, Mohammed, B. Selma, Eagon, J. Christopher, Hotamisligil, Gökhan S., Klein, Samuel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646068/ https://www.ncbi.nlm.nih.gov/pubmed/19066313 http://dx.doi.org/10.2337/db08-1220 |
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